Machine: DSC-Modulated Q2000 TA Instrument/TGA Q5000 TA Instrument Unit: Pharmaceutics and biopharmaceutics |
- DSC-Modulated Q2000 TA Instrument
Observation of endothermes and exothermes (fusion, cristallisation, evaporation, dissolution, degradation)
Phase-transition temperatures (amorphe, cristalized, lipids)
Assessment of the drugs/excipients compatibility or interaction
Protein degradation and denaturation assessment – Amorphous structure: determination of the glass transition, detection of amorphous material in semi-crystalline compound. – Crystallinity: Melting and crystallisation, Purity, Polymorphs
- TGA Q5000 TA Instrument
Quantification of residual solvants
Assessment of degradation and loss of volatil residues